More bad news for Nalgene

Byoliveridley

Nalgene, and other so called safe hard plastics made from polycarbonates. Read here for background and all previous Bisphenol A postings.

PLoS Genetics – Bisphenol A Exposure In Utero Disrupts Early Oogenesis in the Mouse

In the course of studies to assess the effects of BPA on the mouse oocyte, we have uncovered a novel “grandmaternal” effect: exposure to BPA during pregnancy disturbs oocyte development in unborn female fetuses. When these fetuses reach adulthood, the perturbations are translated into an increase in chromosomally abnormal eggs and embryos. Thus, low-dose BPA exposure during pregnancy has multigenerational consequences; it increases the likelihood of chromosomally abnormal grandchildren. Our studies also provide mechanistic insight, and, surprisingly, suggest that BPA acts in the fetal ovary not by mimicking the actions of estrogen but by interfering with the function of one of the known estrogen receptors. Thus, our data suggest that estrogen plays a far earlier role in oocyte development than previously suspected and, importantly, raise the possibility that a variety of substances—both synthetic and naturally occurring—that mimic the actions of estrogen or act as estrogen antagonists may affect early oocyte development.

Once again, caution is involved in the interpretation of the results, mice are more sensitive than humans to environmental exposures. The heartening part of this, and other recent studies is that work is now being carried out at doses that are more representative of ambient exposures, making results much more relevant. The part in bold is equally interesting. Estrogen is a very powerful hormone that has so many unknown effects on the body (and the mind, presumably :-;)

Similar Posts

  • Acrolein Main Cigarette Culprit?

    Byoliveridley

    Chemical & Engineering News: Latest News – Cigarettes’ Smoking Gun?

    Acrolein, one of the 4,000 constituents of cigarette smoke, has been found unexpectedly to cause DNA damage in the gene for the infamous tumor-suppressor p53, which is often disrupted by cancer. In particular, the pattern of DNA mutations caused by acrolein mimics what is often found in human lung cancer samples (Proc. Natl. Acad. Sci. USA, DOI: 10.1073/pnas.0607031103).

    “If cigarette smoke is the weapon that causes lung cancer, then these mutations are fingerprints on the knife,” says author Moon-shong Tang of New York University School of Medicine, in Tuxedo. Tang was also involved in identifying another cigarette-smoke component that can induce such mutations: a metabolite of a polycyclic hydrocarbon called benzo[a]pyrene. Acrolein is present in cigarette smoke in levels of up to 1,000 times greater than benzo[a]pyrene.

    So, if you remove acrolein from tobacco smoke, does that make for a much safer smoking experience? Is this a research question worth answering? FYI, I watched Thank You for Smoking last night, so, fresh on my mind!

  • Corn Can't Solve Our Problem – washingtonpost.com

    Byoliveridley

    A must read for anyone who likes articulate scientists writing very approachable articles about important subjects!
    Corn Can’t Solve Our Problem – washingtonpost.com

    If every one of the 70 million acres on which corn was grown in 2006 was used for ethanol, the amount produced would displace only 12 percent of the U.S. gasoline market. Moreover, the “new” (non-fossil) energy gained would be very small — just 2.4 percent of the market. Car tune-ups and proper tire air pressure would save more energy.

    Proper tire pressure is not sexy, and does not lead to billions of dollars of profits!

    The net effect is that ethanol from corn grown in the Corn Belt does increase atmospheric greenhouse gases, and this increase is only about 15 percent less than the increase caused by an equivalent amount of gasoline

    Corn is such a boondongle, it’s amazing what the ADMs and Monsantos of the world can do.

    This means that when tropical woodland is cleared to produce sugar cane for ethanol, the greenhouse gas released is about 50 percent greater than what occurs from the production and use of the same amount of gasoline. And that statistic holds for at least two decades.

    Brazil will not solve all your problems (unless they’re samba related!). Increased demand for ethanol from Brazil could lead to clearcutting of the rain forest/other fallow grassland.

    Across the full process of growing high-diversity prairie hay, converting it into an energy source and using that energy, we found a net removal and storage of about a ton and a half of atmospheric carbon dioxide per acre. The net effect is that ethanol or synthetic gasoline produced from this grass on degraded land can provide energy that actually reduces atmospheric levels of carbon dioxide.

    It’s a very well written article.

  • Do Voluntary Environmental Programs Work?

    Byoliveridley

    Through the most excellent Environmental Valuation & Cost-Benefit News blog comes notice of a book that answers a question that’s been on my mind off and on.

    Environmental Valuation & Cost-Benefit News – Post details: Reality Check: The Nature and Performance of Voluntary Environmental Programs in the United States, Europe, and Japan

    Despite a growing theoretical literature trying to explain how and why voluntary programs might be effective, there is limited empirical evidence on their success or the situations most conducive to the approaches. Even less is known about their cost-effectiveness.

    The book’s called Reality Check (and long byline) and at $40 is too expensive for a look see! But here’s a teaser:

    The central goals of Reality Check are understanding outcomes and the relationship between outcomes and design. Most of the programs it studies have positive results, but they are small compared with business-as-usual trends and the impact of other forces–such as higher energy prices. Importantly, potential gains may be quickly exhausted as the “low-hanging fruit” is picked up by voluntary programs. By including in-depth analyses by experts from the U.S., Europe, and Japan, the book advances scholarship and provides practical information for the future design of voluntary programs to stakeholders and policymakers on all sides of the Atlantic and Pacific.

    So, the answer is no, I guess. Voluntary programs catch the bulk of changes that can be carried out easily anyway and may have been part of the company plans. They also make for good Company PR. The greater the threat of regulation and good enforcement, I guess, the more power you have to set up a good voluntary program. But if it is all carrot and no stick, who knows…

    For an example of what a voluntary program looks like, here’s Climate Wise from the EPA.

  • Solar plant cheaper than conventional plants

    Byoliveridley

    Generating clean electricity that's as cheap as power from fossil fuels is the Holy Grail of green-energy companies. A new solar project powering California homes appears to be closing in on that prize.

    Sempra Generation, a subsidiary of Sempra Energy in San Diego, just took the wraps off a 10-megawatt solar farm in Nevada. That's small by industry standards, enough to light just 6,400 homes. But the ramifications are potentially huge.

    A veteran analyst has calculated that the facility can produce power at a cost of 7.5 cents a kilowatt-hour, less than the 9-cent benchmark for conventional electricity.If that’s so, it marks a milestone that renewable fans have longed for: “grid parity,” in which electricity from the sun, wind or other green sources can meet or beat the price performance of such carbon-based fuels as coal and natural gas.

    via Los Angeles Times: Sempra solar energy project makes advances in costs.

    This is great as long as the math is real. The company has made quite a few changes from conventional solar, including using cadmium telluride as the semiconductor instead of the more expensive polycrystalline silicon and fashioning them into thinner films.

    I am not a big fan of unverified claims, especially when so much money is likely to be involved. But the exact number is not important. This installation appears to get close to or greater than grid parity without the externalities of fossil fuel power generation (carbon costs, mercury mitigation, etc.) being accounted for on the “conventional” side.

    The future appears to be sunny!

    One small, niggling issue, can we stop calling coal “conventional”? Coal comes from the remains of prehistoric plants that made all their biomass by using the sun as a fuel source, got buried way underground, and, after millions of years at high pressure and no oxygen, formed a carbon rich material that if burned, releases a small fraction of the energy that the sun put in it! As such, using the sun directly as a power source is about as conventional as it gets, everything else is 2nd order, derivative and fairly inefficient.

  • Sethusamudram – A typical Indian development project

    Byoliveridley

    The Sethusamudram (bridge sea – for the transliterators) project has the classic development plot lines that I’ve seen play out many times in India. Here’s a rationale from the official site…

    Currently the ships coming from the west coast of India and other western countries with destination in the east coast of India and also in Bangladesh, China etc have to navigate around Srilankan coast. The existing water way is shallow and not sufficient for the movement of ships. This is due to the presence of a shallow region known as Adam’s bridge, located southeast of Rameswaram near Pamban, which connects the Talimannar Coast of Srilanka

    What? They are going to destroy the bridge that rama and the vanaras built? Look at that picture, (thanks Manitham), can’t you see all the “Vanaras” (this has always struck me as racist – folks showing up from the North and calling the darker skinned Southerners Monkeys! But that is a different rant) running across the very clearly delineated land bridge – It’s fascinating, almost makes me believe that the Ramayana happened as narrated!

    Manitham has a good rundown of the project from an activist standpoint.

    A few points

    • The secrecy and lack of transparency are classic government techniques to control the flow of information and discourse. Every government does it, and the Indian government is no exception.
    • Environmental Impact Assessments are bought and paid for by the funding agency, and are hence essentially unreliable and untrustworthy. I had first hand experience of this when I was a student at IIT Bombay 10 years back.
    • There is a lot of politics involved, the port of Tuthukudi (Tuticorin as the damn Brits say) in Tamil Nadu is a clear winner and Colombo in SriLanka stands to lose revenue. There is also a great deal of Tamil Pride involved
    • Read this excellent article from the climate.lk clearinghouse of articles : There is a security dimension here for India that may have been the actual motivation.
    • The area, due to its sheltering and shallow waters, has a lot of marine life. From a 2004 Deccan Herald Article

    The series of meetings called by the Tuticorin Port Trust chairman in the coastal districts have turned out to be stormy with representatives of political parties shouting down objections from fishermen, who fear the loss of livelihood, and environmentalists who say the project threatens to destroy the Gulf of Mannar Marine Reserve. This reserve is one of India’s most biologically diverse coastal regions.
    Over 3,600 species of plants and animals are found here. It is the first marine biosphere reserve in the South and South-East Asia and is believed to have the highest concentration of seagrass species along India’s coast. It is also among the largest remaining feeding grounds for the globally endangered species dugong. Five different species of endangered marine turtles, innumerable fish, molluscs and crustaceans are also found here. The Bombay Natural History Society (BNHS), the largest NGO working in the field of bio-diversity and environmental conservation, has said the rapid Environmental Impact Assessment (EIA) report prepared by the National Environmental Engineering Research Institute (NEERI) is insufficient and a detailed study should be conducted in all seasons for at least a year.

    • The EIA actually says that since the seaway is 20 km away from the reserve, there will be no effect on the reserve, um, that seems highly unlikely to me…
    • The other major dimension is the usual utter lack of care for the people displaced. previous instances like the Sardar Sarovar project indicate that there will be no fair compensation for the displaced people, or for lost livelihood, which I guess is perfectly fine because it serves the greater good of the country?

    Most of these big projects have resulted in overstated gains, understated losses, and huge wastes of taxpayer money. I don’t trust this to be any different. The facts look fudged, the project seems unnecessary (where’s my tamil pride?) and the effect on the wildlife and the crazy complex current system around Sri Lanka may change significantly leading to unforseen micro climate effects.

    Two thumbs down…

  • |

    One Person's Carbon Offset – Another's Child labor?

    Byoliveridley

    The ‘carbon offset’ child labourers – Times Online

    “Pumping furiously on a foot treadle in the afternoon heat, six-year-old Sarju Ram is irrigating her impoverished family’s field, improving the crop and – without knowing it – helping environmentally sensitive holiday-makers assuage their guilt over long-haul flights to dream destinations.

    But Sarju and her four brothers and sisters working flat out in a clump of trees that provide scant shelter from the sun illustrate a growing argument over claims that British environmentalists’ efforts to curb greenhouse emissions are inadvertently fuelling an increase in child labour.”

    Carbon Offsets are a pricing mechanism setup where people can sign up to pay various companies to compensate for their greenhouse gas emissions by funding mitigation projects, such as planting trees, funding renewable energy projects, and in this case, paying money to farmers (and their families) to pump their water using a foot pump. Terrapass is one such well known company and there are many others.

    I am not so sure I would characterize this as exploitative child labor. There’s plenty of that going around in conventional manufacturing in Asia, not to mention children being used to kill. Compared to this general egregiousness, the prospect of a farmer’s kid, who would be working on the farm anyway, biking away for half an hour so his family can get some extra money does not sound all that bad. Yes, the colonialistic aspects of the story hit me in the face and makes me want to condemn a practice where a rich Westerner pays a poor farmer to pedal away for hours so she can fly to the Galapagos for a eco-vacation.

    But, in the end, these offsets do something. No, they will not do anything to slow (well, maybe a little, imperceptibly, perhaps?) CO2 emissions. Obviously, there’s no substitute to comprehensive worldwide carbon reduction strategy which prices carbon correctly, does not put barriers on technology transfer, and does not transfer greenhouse emissions from the US to Western Europe to China and India in the name of efficiency while doing nothing to ensure that that this manufacturing uses clean technology. Offsets make people aware of their actions, and choices they can make. This makes them (I hope) more likely to support major climate change legislation. It is more about attitudinal change than major change. But calling this child labor and exploitation is, I think, unwarranted.