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South Asians: Watch your Heart

Byoliveridley

Seems like us South Asians die earlier from heart attacks.

ScienceDaily: South Asians Have Higher Levels Of Heart Attack Risk Factors At Younger Ages

Deaths related to cardiovascular disease occur 5 to 10 years earlier in South Asian countries than in Western countries, according to background information in the article. This has raised the possibility that South Asians exhibit a special susceptibility for acute myocardial infarction (AMI; heart attack) that is not explained by traditional risk factors.

But why?

The prevalence of protective risk factors (leisure time physical activity, regular alcohol intake, and daily intake of fruits and vegetables) were markedly lower in South Asian study participants compared with those from other countries.

Um, it is mainly behavioral, not genetic according to the authors, and hence can be mitigated by lifestyle changes.

Well, I guess it is time to take a personal stock as of 1-18-2007:

  • Weight – Well, I am in the lower end of the healthy BMI.
  • Exercise – 4-5 days of 45 minutes – 1 hour per day, pretty good.
  • Food – Well, mostly good, especially if the candy can be avoided. I need to eat more vegetables, but I eat a lot of high fibre, and whole wheat food, probably not enough protein, mostly vegetarian.
  • Alcohol (1-2 drinks is apparently a heart protector) – Amen, I am a religious one drink a day partaker, more on weekends :-;
  • Smoking – Well, gave that up a while back, now to quit that occasional “party” smoke.
  • Stress – Well, not so good, this is probably the area I would need to work on the most.
  • Hypertension – Well, I am borderline on my blood pressure readings 🙁 Need to work on that.
  • Cholesterol – Still waiting for results on my physical.

On the whole, I seem to be in decent shape. It’s good to take stock once in a while.

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    Byoliveridley

    There is nothing like stopping at a gas station somewhere in the Catskills, glancing up at Fox News on TV and finding out that they killed Benazir Bhutto. Of all the Bhutto related articles, this one captured my attention.

    South Asians like their martyrs. My great-grandfather allegedly brought home a vial of some of the ashes of a teenage revolutionary hanged by the British. Khudiram had thrown a bomb at a British magistrate and gone to the gallows with a smile. Ironically, my great-grandfather worked for the British, in their police service. But he was so awed by young Khudiram’s sacrifice, he used his official connections to get that vial, which he kept in his bedroom.

    Benazir was no 15-year-old tilting at windmills in some foolhardy act of defiance. She was South Asian royalty. “Benazir is killed. I’m stunned,” a friend texted me from a cafe in Calcutta. “I really am.” As my friend says, in our feudal societies, much as we might pretend otherwise, we have a royalist streak. And when a royal goes down in a hail of bullets, it sends a collective shiver down our spines.

    Benazir Bhutto, martyr | Salon.com

    He’s right, having grown up through two major assassinations on Indian “royal family” scions (Indira Gandhi and Rajiv Gandhi), the post-martyr deification that occurs needs to be lived through to be understood.

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  • Pakistan helped Kabul terrorist act on Indian Embassy

    Byoliveridley

    American intelligence agencies have concluded that members of Pakistan’s powerful spy service helped plan the deadly July 7 bombing of India’s embassy in Kabul, Afghanistan, according to United States government officials.The conclusion was based on intercepted communications between Pakistani intelligence officers and militants who carried out the attack, the officials said, providing the clearest evidence to date that Pakistani intelligence officers are actively undermining American efforts to combat militants in the region.

    Pakistanis Aided Attack in Kabul, U.S. Officials Say – NYTimes.com

    Not terribly surprising, but it’s the first time they’ve actually been caught on tape helping terrorists. Countries have been invaded on far flimsier pretexts. Luckily, no Americans were harmed in the filming of this movie. So the ISI will just get a slap on the wrist. Of course, as you read the rest of the article, you find out that the mastermind of these attacks, just like most of the other senior militants, was funded and trained by the CIA in the 1980s. So, what good will come out of further American meddling is at this point in time, uncertain.

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    FDA decides to breed super bugs

    Byoliveridley

    Well, what else can you say about it. This is insanely moronic. Read this sierra club release about the overuse of antibiotics brought on by the overcrowding of animals in food production factories (aka “farms”). Read the whole article and see how much everyone will be endangered so that Intervet, Inc. can make money.

    FDA Rules Override Warnings About Drug – washingtonpost.com

    The government is on track to approve a new antibiotic to treat a pneumonia-like disease in cattle, despite warnings from health groups and a majority of the agency’s own expert advisers that the decision will be dangerous for people. The drug, called cefquinome, belongs to a class of highly potent antibiotics that are among medicine’s last defenses against several serious human infections. No drug from that class has been approved in the United States for use in animals.

    Note, a powerful and potent antibiotic that works well, but is not used much because it’s the last line of defense. But the drug company that manufactures this product cares little about long term efficacy. Their only goal is to maximize short term shareholder value. I don’t blame them, I blame the government for not doing its job, that is, to balance these short term and long term goals and protect the people that pay them a lot of money for this protection.

    The wording of “Guidance for Industry #152” was crafted within the FDA after a long struggle. In the end, the agency adopted language that, for drugs like cefquinome, is more deferential to pharmaceutical companies than is recommended by the World Health Organization.

    Cefquinome’s seemingly inexorable march to market shows how a few words in an obscure regulatory document can sway the government’s approach to protecting public health.

    There’s a reason this present U.S government works in secrecy, so these “obscure” (I am sorry, but nothing that directly affects human health can be called obscure) rule changes will not hit the public eye before it’s too late. Apparently, the FDA can now only consider resistance to food borne diseases in considering an application. That’s like saying that a hospital will only treat victims of food borne diseases, so if you catch the cold, we won’t treat you! This is the Food and Drug Adminstration (all food and all drugs), not the food borne disease protection council.

    This drug is absolutely unnecessary for the following reasons:

    1. The disease it treats (respiratory distress in cows) is brought about by insane levels of animal overcrowding
    2. There are currently a dozen antibiotics for this particular problem, none of which are considered susceptible to resistance
    3. The FDA has previous history with similar public health threats with fluoroquinolones
    4. This drug is considered a last resort drug for antibiotic resistant strains of diseases in cancer patients – So strains resistant to this drug will evolve shortly after the antibiotic is overexposed . This is a death sentence for a lot of very vulnerable people.
    5. A similar drug used in Europe for the last 10 years has resulted in an increase in resistant strains of bacteria.

    This is what you get when you vote for an ideology that hates government. You get a government that hates itself and is busy pawning parts of itself off to its cronies.

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    India Rejects Obvious Patents

    Byoliveridley

    Would have been my headline. Apparently, the New York Times byline writer was more concerned about a multi billion dollar company losing a small amount of money than the fact that a different ruling in this case would have made life saving drugs unaffordable for millions of people. When did American newspapers become shills for the elite?

    Setback for Novartis in India Over Drug Patent – New York Times

    Indian companies will be free to continue making less expensive generic drugs, much of which flow to the developing world, after a court rejected a challenge to the patent law on Monday.

    Aid organizations declared the ruling a victory for the “rights of patients over patents,” but the Swiss drug company Novartis, which filed the case, warned that the ruling would discourage investments in innovation and would undermine drug companies’ efforts to improve their products.

    At issue is the degree of innovation required for a drug to be regarded as truly “new”, where there is a significant enough chance for failure that the company would never develop it unless afforded monopoly rights for 10 years. A very well known tactic by drug companies is to make a slightly different formulation of an existing drug, say an extended release form of a drug which takes a little longer to dissolve, and hence is available to the body at a different time. Under US patent law, this qualifies for full patent protection on the extended release form. By now, the science of making an extended release tablet is well known, it’s just a question of formulating the drug with a different set of inactive ingredients that take longer to dissolve, or sometimes, through a differently engineered tablet. The chemistry of this change is predictable, published and not really innovative. Why should these small changes have patent protection?

    Bonus Note: Madras is my home city, so I’m glad it was decided there!

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  • Is Chronic Occupational Pain a Class Issue?

    Byoliveridley

    Americans in households making less than $30,000 a year spend nearly 20% of their lives in moderate to severe pain, compared with less than 8% of people in households earning above $100,000

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    Based on a study published in the Lancet (much moolah required to read, funny that the authors of an article on the class/money based nature of pain would publish in a journal that requires all kinds of money to read, heard of PLOS?), one would have to say yes. People in low paying service jobs don’t have the luxury of mid afternoon yoga, or that once a week massage, or being able to take a “mental health” day, or any such luck. Also, the work is physically demanding, long hours of standing, heavy lifting, and repetitive motions the body was not designed for.

    Krueger notes that the type of pain people reported typically fell on either side of the rich-poor divide. “Those with higher incomes welcome pain almost by choice, usually through exercise,” he says. “At lower incomes, pain comes as the result of work.” Indeed, Krueger and Stone found that blue-collar workers felt more pain, from physical labor or repetitive motion, while on the job

    It is very sad, but a lot of this pain is avoidable. Next time you go to the grocery store, notice that the people at the check out counter stand all the time. Why? What about their job requires continuous standing? I’ve been to other countries, Germany for instance, where they are provided with high chairs that help them move the items from the conveyor through the scanner to the bagging area with much less effort. How many chairs have you seen in a grocery store lately?

    Why can’t this very simple system be implemented? It would provide much relief. Three major issues:

    1. Lack of bargaining power: Unions are a dirty word. Last I heard, the unionization rate in the states was 12%. No one speaks for the cashier. It is considered a low paying, low skill occupation where people can be replaced easily and without “pain”. So, you’re on your own, ask for a chair, and you’ll be seated in one very soon (at home, your ass fired and tired).
    2. Money: And this is linked to point 1. Implementation of any programs designed to make workers’ lives a little easier costs money up front. Since workers are expendable and have no voice, it’s easiest to steal from them and deny them basic comforts.
    3. The American notion of individualism: You deserve what you get based on how hard you work and how intelligent you are. Grocery store cashiers must be lazy and dumb to be where they are. they “deserve it”

    I don’t see it changing at all. But next time you walk into a grocery store and find a rather sullen clerk, it’s not that she’s lazy or has a bad attitude, she may just be in a lot of pain.

    Happy Sunday!

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    CNN Finds Indian Widows Ostracized – 200 years late on the story

    Byoliveridley

    cnnscreenshot.jpg

    Umm, CNN, not exactly headline or breaking news, is it? Raja Ram Mohan Roy crusaded against it in the 1800s, Deepa Mehta made a movie about it recently. So, why was this on my cnn front page? God knows…

    Shunned from society, widows flock to city to die – CNN.com

    Ostracized by society, thousands of India’s widows flock to the holy city of Vrindavan waiting to die. They are found on side streets, hunched over with walking canes, their heads shaved and their pain etched by hundreds of deep wrinkles in their faces.