EU's REACH Program's cornucopia of toxicology data

Byoliveridley

The REACH program from the European Union is an incredibly far reaching (no pun intended, of course!) effort to catalog the effects of chemical compounds on human health. I came across this interesting article at Environmental Science and Technology.

ES&T Online News: Will the EU’s REACH serve researchers’ needs?

Europe’s new chemicals law, REACH (Registration, Evaluation, and Authorisation of Chemicals), will put about $13 billion worth of data on 30,000 substances onto a searchable database made available at no cost on the Internet. It sounds like a dream come true for researchers wanting to design new compounds free of the structures that cause human health hazards. But lack of funding for basic research and concerns about the competence of toxicity tests have dampened expectations among some scientists.

Well, D’uh, any program that big is bound to have some problems. But the shifting of burden of proof away from the regulators to industry is a big deal and will lead to a lot of self regulation. Companies will have to prove that their chemicals are safe.

John Warner, a synthetic organic chemist at the University of Massachusetts, says REACH will be effective at pushing companies to select safer alternatives that are already on the market. But for the many reagents and solvents that have no safe alternatives, safe molecules must be designed, and REACH is not structured to promote the design work, Warner says.

Yes, this is an effort to regulate existing and new chemical entities, not an initiative to spur innovation. From the REACH site:

The REACH Regulation gives greater responsibility to industry
to manage the risks from chemicals and to provide safety information
on the substances. Manufacturers and importers will be required
to gather information on the properties of their substances,
which will help them manage them safely, and to register the
information in a central database.

The innovation is going to be market driven by the fear of this regulation. Maybe we will start calling it OVERREACH!

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    A Company that Specializes in Profiting from Harm

    Byoliveridley

    The LA Times has an interesting investigation on the activities of Amvac.

    Pesticide maker sees profit when others see risks – Los Angeles Times

    Amvac is a leading maker of organophosphates, a class of older, highly toxic pesticides that has been under regulatory scrutiny since the late 1980s. As larger firms have stopped manufacturing some of their organophosphates, Amvac has bought the rights to make or sell 10 of them since 1989, according to company records and interviews. One of them, mevinphos, was banned in the U.S. in 1994 after a study by the U.S. Environmental Protection Agency found that it was responsible for poisoning more field workers in California than any other agricultural chemical. Amvac continues selling the product overseas, according to company officials. Amvac is by no means the largest producer of pesticides that have attracted regulatory scrutiny, but the company stands out for its willingness to embrace chemicals that other firms have abandoned.

    Amvac Slogan

    Love that slogan, don’t ya’! There are so many loopholes in pesticide regulation that a company like Amvac can post impressive profits by using these loopholes, having a significant say in the writing of the regulation, and effortlessly denying and delaying action. It’s a well researched piece, read in full.

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    Hog Factories are Evil Part 1232

    Byoliveridley

    This rather interesting study tracks the movement and evolution of antibiotic resistance from hog cesspools (lagoons) caused by factory production (hog farming) of pig meat. You see, in order to pack that many hogs together and not cause them to keel over and die from disease, they have to be pumped full of antibiotics. Guess where the antibiotics end up? In their “refuse”.

    As always, I leave you with The Meatrix if you want to know more about factory farming.

    Antibiotic Resistance Tracked From Hog Farms to Groundwater

    The routine use of antibiotics in swine production can have unintended consequences, with antibiotic resistance genes sometimes leaking from waste lagoons into groundwater, according to new research from the University of Illinois.

    Researchers report that some genes found in hog waste lagoons are transferred, “like batons,” from one bacterial species to another. This migration across species and into new environments sometimes dilutes, and sometimes amplifies, genes conferring antibiotic resistance, they say.

    The new report, in the August issue of “Applied and Environmental Microbiology,” tracks the passage of tetracycline resistance genes from hog waste lagoons into groundwater wells at two Illinois swine facilities.

    Tetracycline is widely used in swine production. It is injected into the animals to treat or prevent disease, and is often used as an additive in hog feed to boost the animals’ growth.

    Its near-continuous use in some hog farms promotes the evolution of tetracycline-resistant strains in the animals’ digestive tracts and manure.

    This is the first study to take a broad sample of tetracycline resistance genes in a landscape dominated by hog farming, said principal investigator R.I. Mackie, a professor in the University of Illinois-Champaign department of animal sciences and an affiliate of the Institute for Genomic Biology.

  • |

    Melamine – now in Pigs

    Byoliveridley

    The pet food recall gets scarier. The FDA does not have this issue under control. It is not a conspiracy to hide anything, it’s just the pace at which the FDA operates, and its lack of mandate to really regulate animal feed.

    Pet Foods May Have Been Intentionally Poisoned

    The FDA and Agriculture Department also were investigating whether some pet food made by one of the five companies supplied by Wilbur-Ellis was diverted for use as hog feed after it was found unsuitable for pet consumption.

    “We understand it did make it into some hog feed and we are following up on that as well,” Sundlof said.

    Later Thursday, California officials said they believe the melamine at the quarantined hog farm came from rice protein concentrate imported from China by Diamond Pet Food’s Lathrop facility, which produces products under the Natural Balance brand and sold salvage pet food to the farm for pig feed.

    “Although all animals appear healthy, we are taking this action out of an abundance of caution,” State Veterinarian Richard Breitmeyer said in a statement. “It is unknown if the chemical will be detected in meat.”

    Officials are investigating American Hog Farm’s sales records to determine who may be affected by the quarantine, said Steve Lyle, a spokesman for the California Department of Food and Agriculture. The 1,500-animal farm operates as a “custom slaughterhouse,” which means it generally does not supply meat to commercial outlets.

    “Mostly it is not so-called mainstream pork. This is an operation that sells to folks who come in and want a whole pig,” said Lyle said.

    Officials urged those who purchased pigs from American Hog Farm since April 3 to not consume the

    Well, the issue is not the safety of the melamine contaminated pork, the risk to humans is possibly low. The problem is that these ingredients are out of control, and unaccounted for, and being diverted to places they should not be. The systemic flaws are many, and I hope the FDA will issue some new guidelines to tighten up animal feed standards.

    Another tidbit:

    FDA officials would not release the names of the other two manufacturers that Wilbur-Ellis supplied, citing its ongoing investigation

    Is it just me, or does this always happen on a Friday???

  • 'Shocking' conditions at Kenya dump

    Byoliveridley

    B26F0EF1-45A5-4229-9FE0-83784AA06DBC.jpg

    As part of blog action day, today’s a day when every blog features a post about the environment. Turns out that this is an environmental blog where most of the posts are about the environment. But nothing like a deadline for a noble cause to make me blog, so here goes…

    What the rich use and throw away, the poor are reduced to scavenging to earn a meager living. Yes, while climate change rightly takes up a lot of attention, more mundane problems including landfills in poor communities, the export of waste from the first world to the third world, and the “shocking” poverty that drives this export of waste all deserve their fair share of attention.

    U.N.: ‘Shocking’ conditions at Kenya dump – World Environment – MSNBC.com

    “Willis Ochieng, 10, scavenges through smoking refuse piled as high as a house at one of Africa’s biggest rubbish mountains, his friends sitting nearby sucking on dirty plastic bottles of noxious yellow glue.

    Located near slums in the east of the Kenyan capital Nairobi, the open dump receives some 2,000 tons of garbage daily. A U.N. study published on Friday says it is seriously harming the health of children and polluting the city.”

    And boy, do the people there suffer. Asthma, anemia, high levels of lead in the blood, chronic cough, and a smorgasbord of other acute and chronic conditions.

    This dump is not alone, of course. Landfills are a feature of every country, and in my current home state of North Caroiina, are located with disproportionate frequency in African American communities. the free market advocate would say that this represents an opportunity for the people in the community to gain some employment and make some money. The truth of the matter, however, is that we do not pay the right price for waste generation. The people who live near, and make a living off the “dump” subsidize our profligate selves.

  • Today is World Water Day

    Byoliveridley

    World Water Day – World Water Day

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  • BC's Election

    Byoliveridley

    Is over and the centre-right Liberals won. Many in the traditional environmental movement are trumpeting it as a referendum on the BC Carbon Tax. I am not so sure. The so called people who were supposed to vote for the opposition left leaning NDP, but did not because of their (admittedly stupid) opposition to the “gas tax” also gave the Green Party their lowest share of the vote in the last few years. I am finding it hard to imagine a left leaning voter voting for the Liberals instead of the NDP, rather than throwing her vote on the Green Party.

    The truth is probably a lot simpler. Carole James of the NDP did not resonate with voters as an alternative for many reasons, poor campaign positioning, lack of vision, poor media coverage, etc. and in tough economic times, BC just made what it considered a safe choice.

    Of course, BC also made a “safe” choice and rejected a proportional representation system for the province. More will be known once any exit poll data is released, but a proposal which came within a couple of percentage points of passing in the last election failed roundly this time. There is early speculation that it was how the question was asked. I would have preferred a multi-party proportional system to reduce the stranglehold of the two major parties and get some Green Party representation in the legislature.

    Anyway, full speed ahead for BC’s puny Carbon Tax, which will go all the way to $30 a ton in a couple of years, let’s see what that does to compensate for The Liberal’s penchant for massive road building, offshore drilling ideas and “business friendly” privatization of the commons approach to governance.

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