Conflicts of Interest in Bisphenol A Decision Making

I have written about bisphenol A recently. It’s a chemical found in polycarbonate plastics that has been linked with some crazy effects in mice at ambient levels including disruption of oogenesis (egg production) and effects two generations removed (grandmother effects).

Public health agency linked to chemical industry – Los Angeles Times

For nearly a decade, a federal agency has been responsible for assessing the dangers that chemicals pose to reproductive health. But much of the agency’s work has been conducted by a private consulting company that has close ties to the chemical industry, including manufacturers of a compound in plastics that has been linked to reproductive damage.

In 1998, the Center for the Evaluation of Risks to Human Reproduction was established within the National Institutes of Health to assess the dangers of chemicals and help determine which ones should be regulated. Sciences International, an Alexandria, Va., consulting firm that has been funded by more than 50 industrial companies, has played a key role in the center’s activities, reviewing the risks of chemicals, preparing reports, and helping select members of its scientific review panel and setting their agendas, according to government and company documents.

This kind of work is too important to be left to contractors like Sciences International (however good they may be), which also has contracts with companies that manufacture and market products containing Bisphenol A. It’s very simple, most companies, for profit entities and even non-profits dependent on funding sources tend to maximize short term gain over long term good. While the political arm of the government does that as well, the institutions stable enough to do reliable work on policy issues that affect our long term well being are few in number. Government run research with stable funding, good employees and good management will do this work well, it’s a good match between the nature of the work and the nature of the organizations.

The ever excellent Pump Handle has more, I read their post as I was writing this one and so, nothing more to say, really, except, remember Children of Men! Fertility is not to be toyed with, any chemical that has the ability to affect egg production two generations down needs to be handled with care. 

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  • Benzene in soft drinks – Flavor of the Month?

    Benzene Levels in Soft Drinks Above Limit – Yahoo! News

    WASHINGTON – Cancer-causing benzene has been found in soft drinks at levels above the limit considered safe for drinking water, the Food and Drug Administration acknowledged Wednesday.
    Even so, the FDA still believes there are no safety concerns about benzene in soft drinks, or sodas, said Laura Tarantino, the agency’s director of food additive safety.”We haven’t changed our view that right now, there is not a safety concern, not a public health concern,” she said. “But what we need to do is understand how benzene forms and to ensure the industry is doing everything to avoid those circumstances.”

    The admission contradicted statements last week, when officials said FDA found insignificant levels of benzene.

    In fact, a different study found benzene at four times the tap water limit, on average, in 19 of 24 samples of diet soda.

    The formation of benzene in soft drinks is from the reaction of ascorbic acid (aka Vitamin C) and benzoate salts, notably sodium benzoate which is used as a preservative. As the FDA letter states:

    We learned that elevated temperature and light can stimulate benzene formation in the presence of benzoate salts and vitamin C, while sugar and EDTA salts inhibit benzene formation.

    Is this a pressing concern? First of all, exposure modeling done by the EPA indicates that 93% of all benzene exposure is through inhalation (cigarette smoke, indoor offgassing, that wonderful refueling smell!), with 7% exposure through oral ingestion. So, potentially elevated levels in this 7% fraction are not likely to greatly increase exposure. In addition, the 5 parts per billion level for drinking water is set based on an assumed daily consumption of 2 liters per day (Source – USEPA), a safety factor up from the actual estimated 0.9-1.2 L per day measured consumption. Assuming the average amount of benzene in soda (mainly diet, mind you) is 4 times that of drinking water, a 500 ml dose of diet soda per day is required to equal the dose from drinking water, which mind you, only counts for 7% of the total bezene exposure. So in a sense, a person drinking 2 servings of diet soda per day would exceed the exposure from drinking water at the federally regulated level, and knock the socks off the California standard of 0.13 ppb in water. This will increase his/her known oral exposure. The total exposure to benzene of that individual, however, would not go up significantly because the overwhelming majority of the exposure still occurs through the nose, not through the mouth.

    The issue here, and benzene is just the symptom, is that consumers know much more about their drinking water than they do about their manufactured food products, and that is not good for the consumer or for the industry because in the absence of knowledge and full disclosure, both parties are vulnerable. Which is why attempts to limit consumer knowledge hurt everyone.

    Conclusion Please don’t stop drinking soda because of this, I am sure you can find plenty of other reasons to limit your soda consumption… Drink lots of filtered tap water, it’s the best!! And, I can assure you that most tap water is tested thoroughly, it’s zero calories and cheap!

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    James Hansen, the Cliffside power plant and global warming

    James Hansen gave an interesting talk on the physics of climate change, the magnitude of current anthropogenic emissions versus historical CO2 regimes, and the need for immediate action at the NCWarn forum on the Cliffside power plant issue.

    In a CBS 60 Minutes profile in March 2006, Hansen said, “The speed of the natural changes is now dwarfed by the changes humans are making to the atmosphere and the surface.” Carolinas Clean Air and NC WARN are part of a statewide effort by public interest groups to block the new Cliffside plant and help the state reduce greenhouse gases by aggressively ramping up energy efficiency, cogeneration and renewables. That effort has already stopped one of two plants Duke sought to build at Cliffside – by proving it wasn’t needed. The second unit has suffered multiple delays and cost overruns and is the subject of ongoing legal battles over air pollution and water permits.

    Dr.JamesHansenInNC10-07

    Some background: Duke Energy, the North Carolina utility wants to spend a heap of public money building a new coal fired power plant in Cliffside, NC. The problem? They will not sequester or otherwise capture the massive CO2 emissions out of the plant, which is inexcusable given what we know about climate change now.

    Following an excellent talk by Mike Nicklas of Innovative Design, a Raleigh based green architectural firm which focused on reducing demand by increasing efficiency, James Hansen’s talk was an excellent primer on climate change, its history, its easy and basic correlation with atmospheric CO2 concentrations, our current state of affairs, and what we need to do in the next 10 years.

    Their presentations can be found here (Nicklas), and here (Hansen). Go see it. Hansen talked a lot about the interaction of scientists, policy makers and the media in framing the “debate” and contrasted the quick march to consensus on the ozone hole with the the sometimes deliberate fact muddying of the climate debate.

  • USGS Releases Study on US Well Water

    The actual journal paper seems to be behind a subscription wall. But, here’s a summary…

    ScienceDaily: Chemical Quality Of Self-Supplied Domestic Well Water

    Since the water quality of domestic wells is not federally regulated or nationally monitored, this study provides a unique, previously nonexistent perspective on the quality of the self-supplied drinking water resources used by 45 million Americans in the United States. This national reconnaissance study is based on a compilation of existing data from a very large number of wells sampled as part of multiple USGS programs.

    Well water is not held to the same standards as municipal water, which means it is not normally tested for nasties such as arsenic.

    gwmr_89_f4.gif
    Well (no pun intended!), looky here, but arsenic levels in well water exceed EPA Maximum Contaminant Levels (MCLs) more than 10% of the time. If, and this is a big if, you extrapolate these results to the whole country, as much as 5 million people may be exposed to higher than allowed arsenic levels. Arsenic is a notorious contaminant with an MCL of 0.01 mg/L, down a factor of 5 as of January 2006 due to data that indicates effects at even lower doses.

    If I drank well water, I would get it tested for arsenic.

    gwmr_89_f1.png
    Most of the results are from the North East, which means that outside research circles (and behind subscription walls), groundwater arsenic levels could be a significant problem that not too many people are aware of.

    All figures are from the paper.

    Reference

    Focazio, Michael J., Tipton, Deborah, Dunkle Shapiro, Stephanie & Geiger, Linda H. (2006) The Chemical Quality of Self-Supplied Domestic Well Water in the United States. Ground Water Monitoring & Remediation 26 (3), 92-104. doi: 10.1111/j.1745-6592.2006.00089.x

  • Apparently, the Earth is warming up…

    story.global.warming.2.jpgAnd Dog bites man, yet again, it’s amazing how they keep doing that. Think of all the money being wasted on re-proving the obvious, this is money not spent in mitigating the effects, money not spent on research, money not spent on encouraging people to use more efficient lighting… It’s a shame.

    CNN.com – Study: Earth ‘likely’ hottest in 2,000 years – Jun 22, 2006

    Climate scientists Michael Mann, Raymond Bradley and Malcolm Hughes had concluded the Northern Hemisphere was the warmest it has been in 2,000 years. Their research was known as the “hockey-stick” graphic because it compared the sharp curve of the hockey blade to the recent uptick in temperatures and the stick’s long shaft to centuries of previous climate stability.

    The National Academy scientists concluded that the Mann-Bradley-Hughes research from the late 1990s was “likely” to be true, said John “Mike” Wallace, an atmospheric sciences professor at the University of Washington and a panel member. The conclusions from the ’90s research “are very close to being right” and are supported by even more recent data, Wallace said.

    The panel looked at how other scientists reconstructed the Earth’s temperatures going back thousands of years, before there was data from modern scientific instruments.

    For all but the most recent 150 years, the academy scientists relied on “proxy” evidence from tree rings, corals, glaciers and ice cores, cave deposits, ocean and lake sediments, boreholes and other sources. They also examined indirect records such as paintings of glaciers in the Alps.

    Combining that information gave the panel “a high level of confidence that the last few decades of the 20th century were warmer than any comparable period in the last 400 years,” the academy said.

  • Canada's only proposed Carbon Targets in Danger

    Bill C-311, Canada’s Climate Change Accountability Act, is back in the “news” (no silly, not the media, who have more important things to worry about). I had written about this before the Copenhagen meeting. This bill sets Canada up with greenhouse gas emission reduction targets that would put Canada in a respectable mainstream position, 25% below 1990 levels by 2020, 80% below 1990 levels by 2050. But the Conservatives, in one of their classic legislative gambits, have forwarded the vote for April 14th, Wednesday. If the bill doesn’t pass here, it’s dead, and 4 years of countless committee readings, and multiple votes to pass would be wasted. And Canada will not have any climate change legislation whatsoever.

    Serious business, isn’t it? Climate Action has more, including what you need to do (I know, short notice, that’s apparently how important decisions get made around here).

    The Liberals hold the key. It was they who voted with the Conservatives the last time to scuttle the pre-Copenhagen vote. As of writing this post, no official word from the Liberals on their position.

    A call to Michael Ignatieff’s office, (613) 995-9364 gives me little hope of passage. I was told that the MPs had met, that Mr. Ignatieff would not be voting (apparently, because it’s a private member’s bill, leaders don’t vote, weird). Also, the official position of the party is that because it is a private member’s bill, that every MP would be free to vote on their “conscience”. Given that the Liberal party could not even defend women’s health in a recent whipped vote, I wonder where their conscience is on this.

    A call to David McGuinty’s (the Liberal Environmental Critic) Office, (613) 992-3269, elicited the rather helpful response that they would not be commenting on their stand till after the vote.

    Of our local MPs, both Denise Savoie (NDP) and Dr. Keith Martin (Liberal) will be voting to preserve the bill, they are on record saying this at a forum on climate change last week. Of course, Gary Lunn (Conservative) is not part of the equation here, pointless.

    So, call, call and call away, the Liberals need to hear about this. They don’t appear to understand the most basic rule of opposition politics, you get no points for supporting the government, except from pundits in the mainstream media. Only if you inflict some defeats on the government will the people of Canada take you seriously.

    David McGuinty – (613) 992-3269
    Michael Ignatieff – (613) 995-9364

    As always, remember that it is the Liberals that will be blamed for this bill’s demise, we all know the Conservative position on climate change. The NDP and Bloc Quebecois have voted repeatedly to pass this legislation. It is Michael Ignatieff’s Liberals who will stand in the way of Canada’s environmental progress.

  • | |

    Why India is a Prominent Global Warming Sceptic

    I grew up in Chennai, proudly known as the automotive capital of India and home to Standard Motors. While it makes me very happy to see Chennai back on the automotive map, it also points me to the fact that India needs to be involved in the long-term reduction of heat-trapping emissions. This is not going to help…

    BBC NEWS | Business | India eyes 25 million automotive jobs

    India’s labour intensive car industry has become a tremendous job creator and as such a crucial driver of economic growth.

    Already, some 10 million people are working in factories across India – making cars and motorcycles, tractors and trucks – or in sales and service centres.

    And their numbers are set to swell.

    By 2016, the automotive industry should have created employment for 25 million people in India, according to government predictions, set out in its Automotive Mission Plan.

    I realize that India has a loooooooooooooong way to go before it catches up with the US and the rest of the developed world as far as per capita heat-trapping emissions are concerned. I also admit that infrastructure development, job creation, manufacturing prowess, etc., are critical for India in order to mitigate its soul crushingly large poverty and development issues. But, by putting so much emphasis on conventional car technology, and putting so many more CO2 emitting monsters on the road, India is putting itself in a position of playing the development vs. environment game.

    Is it necessary that India and China tread the same path as the U.S and Europe? Does India have to make and use cars that are built using technology developed prior to our knowledge of global warming? The same company that gets cautious praise from the Union of Concerned Scientists for its “leadership” role in global warming will turn around and build factories in India that carry the status quo forward for another 30 years. When you’re starting from the foundation, and you know that the plans provided to you will lead to your house crumbling in 20 years, would you use the plans anyway because your contractor provides you with no alternative? The logical answer seems to be no, but is this process logic driven, or enforced by the existing power structure?

    The vehicle industry is entrenched in the US and therefore, resistant to change. It is understandable, not optimal, not desirable, shortsighted, etc., but understandable. Change requires effort, and a lot of the time, the effort is motivated by external factors, such as strict regulation. Without these external factors, it is very easy to keep chugging along merrily.

    But, does India have to make the same mistakes? Does India have a choice here? I am afraid not. The pressure to build infrastructure quickly leads India to seek foreign investment and the investment will only come in the way of companies like Ford. And Ford will do exactly what it needs to do to make money in the short term (apparently, they’re not very good at that either!).

    What is the answer? The developed countries have to pass legislation that pretty much forces the car companies’ hand. Strict increases in fuel economy standards, tightening of loopholes, and strict enforcement are all required. As this UCS report shows, fuel efficiency improvements of up to 40% are possible using run of the mill technology (as in, no hybrids, no electrics, nothing). But this is not sufficient. While the US market is focused enough that the highest regulation (California) pretty much drives the market, will car companies simply make a set of third world cars and a set of first world cars?

    There’s clearly another piece to the puzzle, encouraging technology transfer of the most carbon efficient technologies to emerging markets so that they can build infrastructure correctly, using current knowledge instead of following the only blueprint currently available to them. Yes, this hits upon intellectual property issues at times, but when your village is being submerged by the sea, intellectual property needs to take a back seat. This technology transfer needs to happen either through incentives (tax breaks, non-profit/UN funding), or disincentives (carbon taxes, etc.). the Kyoto Protocol does have some technology transfer programs built in, but without the participation of the US, the protocol is not going to work.

    Do I see any of this happening? Not really, so I guess we’re stuck with recycled global warming denialism like this one from one of India’s prominent columnists.

    Almost as soon as the Kyoto Protocol on global warming came into effect on February 15, Kashmir suffered the highest snowfall in three decades with over 150 killed, and Mumbai recorded the lowest temperature in 40 years. Had temperatures been the highest for decades, newspapers would have declared this was proof of global warming. But whenever temperatures drop, the press keeps quiet.

    Yes, the country that produces great intellectuals has come down to this. But, this is the prevailing wind in India. As a country, it has swallowed the American line on development being at odds with the environment. As a country, it is poised to greatly increase its heat-trapping emissions and fight vigorously, any efforts to restrict its emissions. India is right in most ways, its per capita energy consumption is miniscule. It already only uses half the energy per dollar of GDP that the US uses (of course, this is at the expense of quality of life for millions). So, any attempts at pointing fingers at China and India are irresponsible. But, that is the past. Looking forward, every country needs to use the most efficient technologies possible, and this Ford factory driven development model ain’t gonna work.

    I leave you with the energy intensity chart…