Melamine movin' on up the food chain

The FDA mentioned recently that the melamine suspected of poisoning many cats had gotten into pig feed in California, well, it gets worse…

Tuesday: Uh-Oh — North Carolina Public Radio WUNC

The FDA announced this afternoon that thousands of hogs in NC and four or five other states are now under quarantine because they were fed tainted rice gluten. Hogs here and in CA have tested positive for melamine. No one knows yet whether it poses any dangers to humans who ate the hogs, but the feds say they’re trying to find out.

At this point in time, I would consider any animal feed from China suspect. Way out of control, because we have no procedure for being proactive about these things…

It won’t amount to much because melamine apparently does not affect humans as much as it seems to affect cats, but it is the utter lack of control of ingredients and raw materials that scares me. What else can sneak through? What if the next one is actually deadly to humans?

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    An off patent miracle cancer cure?

    Interesting news coming out of Canada from a Dr. Anselm at the University of Alberta about a well known chemical dichloroacetic acid (like vinegar with two chlorines!).

    Cheap, safe drug kills most cancers – health – 17 January 2007 – New Scientist

    It sounds almost too good to be true: a cheap and simple drug that kills almost all cancers by switching off their “immortality”. The drug, dichloroacetate (DCA), has already been used for years to treat rare metabolic disorders and so is known to be relatively safe.

    It also has no patent, meaning it could be manufactured for a fraction of the cost of newly developed drugs.

    Here’s the PubMed citation for the article, filled with biology I will have no hope of understanding! I read the press release on sciencedaily a few days back and did a little background digging.

    A clinical trial conducted by Colombia University studying the effects of dichloroacetate on MELAs (stroke like symptoms) was halted early because everyone taking the medication showed significant effects of neural toxicity. This study was commented on by Dr. Anselm who theorized that the effect could be caused by a specific gene mutation not seen in a lot of the patients he works with.

    So, there is some reason for caution on this wonder drug, it may be toxic at certain doses to certain people. Most chemotherapetic drugs are horrendously toxic too. But if this is not a concern, Dr Anselm, meet Sunil Shaunak and his wonderful proposal to setup an alternative pipeline for drug approval that does not involve big/small pharma. I Am sure between Bill Gates, or George Soros, a few million bucks can be rustled up for a cancer cure.

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    Gaping Reminders of Aging and Crumbling Pipes – New York Times

    Gaping Reminders of Aging and Crumbling Pipes – New York Times

    Local and state officials across the country say thousands of miles of century-old underground water and sewer lines are springing leaks, eroding and — in extreme cases — causing the ground above them to collapse. Though there is no master tally of sinkholes, there is consensus among civil engineers and water experts that things are getting worse.

    The Environmental Protection Agency has projected that unless cities invest more to repair and replace their water and sewer systems, nearly half of the water system pipes in the United States will be in poor, very poor or “life elapsed” status by 2020.

    Yes, sewers are unsexy, there’s no new fancy science involved. But water and sewer systems are the very basis of public health, and the biggest reason why Americans don’t die of sleeping sickness and dengue fever (or their subtropical equivalents) in large numbers evey year. People who want to cut taxes and limit government need to keep this in mind. There’s no money to be made out of building and maintaining sewers, it’s a dirty job and government has to do it, or else nobody will, and money is required. We produce the waste, we need to be taxed appropriately for it. It’s that simple.

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    NC Smoking ban now inevitable?

    Well, it has taken less than a decade (I am a pessimist), but looks like smoking in bars and restaurants may finally be over and done with in my old home state of NC.

    Note that there is currently a HUGE loophole in the senate version of the bill, it permits smoking in “private clubs”. Many bars in NC designate themselves as “private clubs” to circumvent prohibition era (or thereabouts) laws that mandate liquor serving establishments to get a certain percentage of their revenue from food. So, my favourite Chapel Hill drinking establishment, The Dead Mule (no website, sorry!) is supposedly a “private club” – You supposedly pay a one time membership fee (usually less than 5 bucks), and are supposed to “sign in” any members and guests. This was all a farce anyway, and the Mule got extremely smoky, it was quite disgusting after a while.

    One hopes that the final bill will make the ban universal. Bans like this work best when they don’t favour one group of establishments over the other for no real reason. The people who work at the Dead Mule are equally entitled to clean air.

    1.5 cautious cheers, let’s see what happens in the end…

    The state Senate voted Thursday to ban smoking in bars and restaurants in North Carolina. It set the stage for what would be a historic prohibition of a product that created thousands of jobs, built Duke and Wake Forest universities and has long been an integral part of the culture in the nation's top tobacco-producing state.

    House members passed a tougher version last month, meaning that lawmakers will still have to work out a compromise, assuming the Senate passes the measure in a second vote on Monday. The bill passed Thursday by an eight-vote margin, 26-18, so that seems likely.

    via State Senate OKs smoking ban – Politics – News & Observer.

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    Grad student measures hazardous levels of air pollution at cigar show

    Sure makes my graduate work in air quality seem a little tame!

    The man behind the subterfuge (Researcher 2, male) was Ryan David Kennedy, 34, a scrappy Canadian graduate student with crooked glasses who is studying the impact of tobacco on air quality.He crossed the border at Buffalo on Monday morning and on Tuesday crashed the giant cigar party and trade show sponsored by the publisher of Cigar Aficionado magazine at the Marriott Marquis in Times Square.

    At a Cigar Show, an Air-Quality Scientist Under Deep, Smoky Cover – New York Times

    Well, what did he find? Particulate matter readings four times higher than “hazardous”. Sometimes I think of strapping on a sampler and going to the local bar just out of curiosity. I can leave the bar if it gets smoky, the bartenders and wait staff can’t. I don’t see why this is not a clear case of hazardous working conditions leading to an immediate indoor smoking ban.  but what do I know, I’m just a scientist!

    Happy Thanksgiving.

    Blogged with Flock

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    Bill could block some ads for new drugs – Not so Fast!

    Bill could block some ads for new drugs – Yahoo News

    Pharmaceutical companies could be prohibited from advertising new drugs directly to consumers for the first two years they are on the market under a bill moving through Congress this week.

    The goal, supporters say, is to ensure medicines are safe before allowing industry to promote them to consumers in the hopes they will request prescriptions from doctors.

    But a reduction in TV and print advertising, which helped transform medications for heartburn and arthritis into blockbusters, would be a serious financial blow to drug makers. According to one study, every $1 spent on pharmaceuticals advertising often adds more than $2 in sales.

    While the Food and Drug Administration already screens a small portion of ads voluntarily submitted by drug companies, consumer advocates favor much tougher regulation, arguing that the studies companies use to test the safety of new drugs are not always large enough to spot dangerous side effects.

    “We don’t know, and we won’t know, how truly safe a drug is until it’s been used in millions of people,” said Consumer Reports analyst Bill Vaughan. “The real testing of these drugs takes place after a pill hits the market and that’s why the advertising needs to be regulated.”

    This is pretty significant. Big pharma is increasingly reliant on the blockbuster drug that addresses chronic and/or lifestyle diseases affecting the a large proportion of the affluent adult population. To reach this population, you need to target it with massive advertising blitzes that

    1. Alert you to the fact that you might have a problem – Restless leg syndrome, anyone!. This might be something that may be important, but nothing you might have noticed.
    2. Prod you to get treated for it.
    3. Convince both you and your doctor that the flashy new drug, which is 100 bucks per month is so much better than the other drug that is 10 bucks a month (Not much science is necessary here, just a major advertising blitz and continuous access to doctors through visits, “seminars”. “gifts”, etc.)
    4. Work with insurance companies to make this drug the treatment of choice
    5. Lather, rinse and repeat!

    Note that advertising is a huge part of this circle, and any restrictions to this said advertising will have pharma crying foul, and free speech. Call me old fashioned, but free speech protects an individual from surveillance, imprisonment, torture, execution, etc. by his oppressive government of choice due to views he/she might have and/or express. All corporate speech is regulated by definition because it involves a flow of information from a party that has a knowledge edge to one, that does not. To the extent that corporate speech helps the end user, it is beneficial. To the extent it hurts, it is not. So regulation of this speech should be a line drawn by government/regulating authority based on maximizing the benefit to the consumer, not to the industry.

    Davidson has urged Senate staffers to eliminate the provision on advertising, arguing that the Supreme Court has already struck down similar attempts to regulate commercial speech.

    I do not think that in the current regulatory and judiciary environment, this provision has any chance of passing. As long as “commercial” speech is as free as “individual” speech, we will forever be exploited by organizations that have a knowledge gap on us and use this knowledge gap to make us buy/do things that may not necessarily be in our interest.

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    Black Lung – Miners pay so you can get more coal

    The Pump Handle alerts us to a special report on coal miners and their lungs, not for the faint of heart, but something to keep in mind when you hear the phrases “Cheap Energy” and “coal” in one sentence, it’s not so cheap for these people.

    Black Lung: Dust Hasn’t Settled on Deadly Disease « The Pump Handle

    Louisville-Courier Journal reporters Laura Unger and Ralph Dunlop offer us the voices and faces of miners who are suffering from coal workers’ pneumoconiosis. Their special report, Black Lung: Dust Hasn’t Settled on Deadly Disease, includes an on-line version which features five compelling videos featuring 40- and 50-year old coal miners who are now suffering with the disabling lung disease. Mr. Danny Hall, 56, for example, who is still severely impaired despite receiving a lung transplant says “if I had to do over, I wouldn’t ever go into coal mining.”

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