All eyes on China

Byoliveridley

First it was the melamine. Then this weekend, there was that horrible story about deaths in Panama linked to the use of diethylene glycol in cough syrup. Now, pigs are dying mysteriously.

Epidemic Is Killing Pigs in Southeastern China – New York Times

Hong Kong television broadcasts and newspapers were full of lurid accounts today of pigs staggering around with blood pouring from their bodies in Gaoyao and neighboring Yunfu, both in Guangdong Province. The Apple Daily newspaper said that as many as 80 percent of the pigs in the area had died, that panicky farmers were selling ailing animals at deep discounts and that pig carcasses were floating in a river.

Lovely. China has exploded out of the gate with its development and incredible growth. But its infrastructure, bureaucracy, attitudes, government accountability and transparency are obviously way behind. The whole world faces the consequences of this lag. But my guess is that it is the rural Chinese and the ones who have been “left behind” that suffer the most, something to keep in mind I guess as people rush to blame China for yet another safety issue. We have the option of being more careful, the rural Chinese don’t.

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  • Autism epidemic not caused by shifts in diagnoses; environmental factors likely

    Byoliveridley

    California’s sevenfold increase in autism cannot be explained by changes in doctors’ diagnoses and most likely is due to environmental exposures, University of California scientists reported. The scientists who authored the new study advocate a nationwide shift in autism research to focus on an array of potential factors in the environment that babies and fetuses are exposed to, including pesticides, viruses and chemicals in household products.

    Autism epidemic not caused by shifts in diagnoses; environmental factors likely — Environmental Health News

    One of the most common arguments you will see about a lot of mental health diagnoses is that doctors have changed their diagnostic practices significantly. While there is evidence of this occurring in diagnoses of childhood depression, anxiety, or even bipolar disorder due to the millions of dollars involved in medication and the attendant corruption, autism is different.

    This population study used 17 year data in California and concluded that diagnostic changes were only responsible for a 2 fold increase, not the seven fold increase seen. The rest is unexplained, and the authors attribute it to a confluence of environmental and genetic factors.

    And no, for the last time, VACCINES DO NOT CAUSE AUTISM!

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    NC Smoking ban now inevitable?

    Byoliveridley

    Well, it has taken less than a decade (I am a pessimist), but looks like smoking in bars and restaurants may finally be over and done with in my old home state of NC.

    Note that there is currently a HUGE loophole in the senate version of the bill, it permits smoking in “private clubs”. Many bars in NC designate themselves as “private clubs” to circumvent prohibition era (or thereabouts) laws that mandate liquor serving establishments to get a certain percentage of their revenue from food. So, my favourite Chapel Hill drinking establishment, The Dead Mule (no website, sorry!) is supposedly a “private club” – You supposedly pay a one time membership fee (usually less than 5 bucks), and are supposed to “sign in” any members and guests. This was all a farce anyway, and the Mule got extremely smoky, it was quite disgusting after a while.

    One hopes that the final bill will make the ban universal. Bans like this work best when they don’t favour one group of establishments over the other for no real reason. The people who work at the Dead Mule are equally entitled to clean air.

    1.5 cautious cheers, let’s see what happens in the end…

    The state Senate voted Thursday to ban smoking in bars and restaurants in North Carolina. It set the stage for what would be a historic prohibition of a product that created thousands of jobs, built Duke and Wake Forest universities and has long been an integral part of the culture in the nation's top tobacco-producing state.

    House members passed a tougher version last month, meaning that lawmakers will still have to work out a compromise, assuming the Senate passes the measure in a second vote on Monday. The bill passed Thursday by an eight-vote margin, 26-18, so that seems likely.

    via State Senate OKs smoking ban – Politics – News & Observer.

  • | | |

    Diacetyl hits the big time

    Byoliveridley

    It’s well known that occupational exposure to various pollutants including pesticides, manufacturing raw materials, and in this case, flavoring agents, is a serious problem affecting millions of factory and farm workers all over the world.

    Which is why it is interesting when one case of a man contracting an illness possibly linked to at-home diacetyl exposure makes much more splashy news than the well documented cases of many workers dying of such exposure at work. It is unfortunate, but people working at factories and in farms are somehow expected to handle higher levels of exposure and risk. The assumption is that they are protected by agencies such as OSHA, and that they will provided with protective wear, etc. But, when the agencies drop the ball on protecting workers, it takes an “escape” of the incident into the ambient realm for the news agencies to pick it up as a headline.

    I guess the good thing now is that this diacetyl issue is blown open, and should result in reform, because alternatives are available.

    Doctor Links a Man’s Illness to a Microwave Popcorn Habit – New York Times

    A fondness for microwave buttered popcorn may have led a 53-year-old Colorado man to develop a serious lung condition that until now has been found only in people working in popcorn plants.

    Lung specialists and even a top industry official say the case, the first of its kind, raises serious concerns about the safety of microwave butter-flavored popcorn.

    “We’ve all been working on the workplace safety side of this, but the potential for consumer exposure is very concerning,” said John B. Hallagan, general counsel for the Flavor and Extract Manufacturers Association of the United States, a trade association of companies that make butter flavorings for popcorn producers. “Are there other cases out there? There could be.”

    A spokeswoman for the Food and Drug Administration said that the agency was considering the case as part of a review of the safety of diacetyl, which adds the buttery taste to many microwave popcorns, including Orville Redenbacher and Act II.

    Meanwhile, ConAgra, the biggest manufacturer of popcorn, announces plans to drop diacetyl at some undetermined “later date”. Weird, their website’s currently down!

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    NC House Smoking Bill passes committee

    Byoliveridley

    Updates on the smoking bills I mentioned last week….

    Bill Would Extinguish Indoor Smoking Statewide :: WRAL.com

    Dismissing North Carolina’s heritage as a tobacco state, a House committee on Tuesday passed a far-reaching indoor smoking ban.

    The Judiciary Committee passed the ban by a 9-4 vote. The measure would prohibit smoking in all indoor workplaces in North Carolina, including bars and restaurants. The rules also would apply to private clubs, except those with nonprofit or tax-exempt status.

    The measure would be complaint-driven — local health departments would act on complaints from the public — and violators would first receive warnings.

    “This was a significant and important event to advance the public’s health in North Carolina,” said Dr. Leah Devlin, director of the state Division of Public Health.

    But critics of the legislation, House Bill 259, pointed out that it faces an uphill battle on the House and Senate floors.

    “What they really want is a complete prohibition of indoor smoking in North Carolina,” said state Rep. Paul Stam, R-Wake. “We all know smoking is nasty and dangerous. The question is whether, in a free society, you let people do some things that are nasty and dangerous.”

    Some opponents said passing the bill could set the stage for similar bans inside personal vehicles and homes.

    “You want to smoke and you own the building. Is it really that bad for the public?” asked state Rep. Ronnie Sutton, D-Robeson.

    Yes Paul and Ronnie, not only did you construct a straw man, you blew smoke on it, gave it lung cancer, tortured it with cigarette butts and finally set it on fire. Sheesh, what asses.

    Update

    From Laura Leslie, WUNC (our local NPR affiliate) reporter who maintains a reporter’s blog at WUNC

    Under the current version of the bill, which isn’t available on the web just yet, only NON-profit clubs could allow smoking – like the Elks Lodge, for example.

    So for the standard nightclub or bar, smoking would be banned.

    Hope it helps – and thanks very much for reading!!
    Laura

    So, that’s a lot of progress on the house bill, making it very close to the senate bill.

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    An off patent miracle cancer cure?

    Byoliveridley

    Interesting news coming out of Canada from a Dr. Anselm at the University of Alberta about a well known chemical dichloroacetic acid (like vinegar with two chlorines!).

    Cheap, safe drug kills most cancers – health – 17 January 2007 – New Scientist

    It sounds almost too good to be true: a cheap and simple drug that kills almost all cancers by switching off their “immortality”. The drug, dichloroacetate (DCA), has already been used for years to treat rare metabolic disorders and so is known to be relatively safe.

    It also has no patent, meaning it could be manufactured for a fraction of the cost of newly developed drugs.

    Here’s the PubMed citation for the article, filled with biology I will have no hope of understanding! I read the press release on sciencedaily a few days back and did a little background digging.

    A clinical trial conducted by Colombia University studying the effects of dichloroacetate on MELAs (stroke like symptoms) was halted early because everyone taking the medication showed significant effects of neural toxicity. This study was commented on by Dr. Anselm who theorized that the effect could be caused by a specific gene mutation not seen in a lot of the patients he works with.

    So, there is some reason for caution on this wonder drug, it may be toxic at certain doses to certain people. Most chemotherapetic drugs are horrendously toxic too. But if this is not a concern, Dr Anselm, meet Sunil Shaunak and his wonderful proposal to setup an alternative pipeline for drug approval that does not involve big/small pharma. I Am sure between Bill Gates, or George Soros, a few million bucks can be rustled up for a cancer cure.

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    PFOA emissions from Non stick cookware and Popcorn Bags

    Byoliveridley

    Important research coming out of NY. See here for previous PFOA posts. Perfluorinated compounds are used in the manufacture of Teflon, and are bioaccumulative. The theory is that the salts left over in the manufacture (residuals) are offgassing during use, and exposing consumers to bioaccumulative compounds.

    Cast Iron, anyone!!

    Quantitation of Gas-Phase Perfluoroalkyl Surfactants and Fluorotelomer Alcohols Released from Nonstick Cookware and Microwave Popcorn Bags

    Fluoropolymer dispersions are used for coating certain cookware products and food-contact packaging to impart oil and water repellency. Since salts of perfluorooctanoic acid (PFOA) are used as a processing aid in the manufacture of many fluoropolymers, it is necessary to determine if these compounds are still present as residuals after the process used to coat nonstick cookware or packaging, and could be released during typical cooking conditions. In this study, we identified and measured perfluoroalkyl carboxylates (PFCAs), particularly PFOA, and fluorotelomer alcohols (FTOHs; 6:2 FTOH and 8:2 FTOH), released from nonstick cookware into the gas phase under normal cooking temperatures (179 to 233 C surface temperature). PFOA was released into the gas phase at 7-337 ng (11-503 pg/cm2) per pan from four brands of nonstick frying pans. 6:2 FTOH and 8:2 FTOH were found in the gas phase of four brands of frying pans, and the sources of FTOHs released from nonstick cookware are under investigation. We observed a significant decrease in gas-phase PFOA following repeated use of one brand of pan, whereas the other brand did not show a significant reduction in PFOA release following multiple uses. PFOA was found at >5 ng during the fourth use of both brands of pans. FTOHs were not found after the second use of either brand of pans. PFOA was found at 5-34 ng in the vapors produced from a prepacked microwave popcorn bag. PFOA was not found in the vapors produced from plain white corn kernels popped in a polypropylene container. 6:2 FTOH and 8:2 FTOH were measured in the vapors produced from one brand of prepacked microwave popcorn at 223 ± 37 ng and 258 ± 36 ng per bag, respectively, but not measured at >20 ng (LOQ) in the other two brands. On the packaging surface of one brand of microwave popcorn several PFCAs, including C5-C12, 6:2 FTOH, and 8:2 FTOH, were found at concentrations in the order of 0.5-6.0 ng/cm2. This study suggests that residual PFOA is not completely removed during the fabrication process of the nonstick coating for cookware. They remain as residuals on the surface and may be off-gassed when heated at normal cooking temperatures.

    More later.