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  • Folklore Based Medicine?

    Breast cancer theory supports African folklore – CNN.com

    While they stressed that women should always get screening and quick treatment for breast cancer, they said their theory could also help explain the belief, widespread in parts of Africa and the United States, that removing a tumor can hasten death. “I must say that I am sure there is more to this than just a myth,” said Michael Retsky of Children’s Hospital and Harvard Medical School in Boston, Massachusetts. His latest hypothesis, which he admits is not supported by any new direct research, is published in the International Journal of Surgery. He stressed that any woman with breast cancer should get the tumor removed. And he noted that in the United States, the women who could be considered at risk of having their cancer spread now get chemotherapy anyway, which would stop cancer’s spread.

    Note, no direct evidence, no double blind trial, just a story? C’mon, you’re a Doctor. Surely, you know that CNN and the other media will take your qualifications, reservations and cautions  and shove them up your you know what to get a nice headline. Most people don’t read past the first two lines anyway, so nothing you say about your reservations will be transmitted to the public.

    I hope you get the funding to prove/disprove your contention. Race based differences in treatment outcomes are not well studied, and are potentially very important. It is vital that more people look at this issue. But speculation based on modeling studies does not belong on CNN.

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    PFOA emissions from Non stick cookware and Popcorn Bags

    Important research coming out of NY. See here for previous PFOA posts. Perfluorinated compounds are used in the manufacture of Teflon, and are bioaccumulative. The theory is that the salts left over in the manufacture (residuals) are offgassing during use, and exposing consumers to bioaccumulative compounds.

    Cast Iron, anyone!!

    Quantitation of Gas-Phase Perfluoroalkyl Surfactants and Fluorotelomer Alcohols Released from Nonstick Cookware and Microwave Popcorn Bags

    Fluoropolymer dispersions are used for coating certain cookware products and food-contact packaging to impart oil and water repellency. Since salts of perfluorooctanoic acid (PFOA) are used as a processing aid in the manufacture of many fluoropolymers, it is necessary to determine if these compounds are still present as residuals after the process used to coat nonstick cookware or packaging, and could be released during typical cooking conditions. In this study, we identified and measured perfluoroalkyl carboxylates (PFCAs), particularly PFOA, and fluorotelomer alcohols (FTOHs; 6:2 FTOH and 8:2 FTOH), released from nonstick cookware into the gas phase under normal cooking temperatures (179 to 233 C surface temperature). PFOA was released into the gas phase at 7-337 ng (11-503 pg/cm2) per pan from four brands of nonstick frying pans. 6:2 FTOH and 8:2 FTOH were found in the gas phase of four brands of frying pans, and the sources of FTOHs released from nonstick cookware are under investigation. We observed a significant decrease in gas-phase PFOA following repeated use of one brand of pan, whereas the other brand did not show a significant reduction in PFOA release following multiple uses. PFOA was found at >5 ng during the fourth use of both brands of pans. FTOHs were not found after the second use of either brand of pans. PFOA was found at 5-34 ng in the vapors produced from a prepacked microwave popcorn bag. PFOA was not found in the vapors produced from plain white corn kernels popped in a polypropylene container. 6:2 FTOH and 8:2 FTOH were measured in the vapors produced from one brand of prepacked microwave popcorn at 223 ± 37 ng and 258 ± 36 ng per bag, respectively, but not measured at >20 ng (LOQ) in the other two brands. On the packaging surface of one brand of microwave popcorn several PFCAs, including C5-C12, 6:2 FTOH, and 8:2 FTOH, were found at concentrations in the order of 0.5-6.0 ng/cm2. This study suggests that residual PFOA is not completely removed during the fabrication process of the nonstick coating for cookware. They remain as residuals on the surface and may be off-gassed when heated at normal cooking temperatures.

    More later.

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    Hog Factories are Evil Part 1232

    This rather interesting study tracks the movement and evolution of antibiotic resistance from hog cesspools (lagoons) caused by factory production (hog farming) of pig meat. You see, in order to pack that many hogs together and not cause them to keel over and die from disease, they have to be pumped full of antibiotics. Guess where the antibiotics end up? In their “refuse”.

    As always, I leave you with The Meatrix if you want to know more about factory farming.

    Antibiotic Resistance Tracked From Hog Farms to Groundwater

    The routine use of antibiotics in swine production can have unintended consequences, with antibiotic resistance genes sometimes leaking from waste lagoons into groundwater, according to new research from the University of Illinois.

    Researchers report that some genes found in hog waste lagoons are transferred, “like batons,” from one bacterial species to another. This migration across species and into new environments sometimes dilutes, and sometimes amplifies, genes conferring antibiotic resistance, they say.

    The new report, in the August issue of “Applied and Environmental Microbiology,” tracks the passage of tetracycline resistance genes from hog waste lagoons into groundwater wells at two Illinois swine facilities.

    Tetracycline is widely used in swine production. It is injected into the animals to treat or prevent disease, and is often used as an additive in hog feed to boost the animals’ growth.

    Its near-continuous use in some hog farms promotes the evolution of tetracycline-resistant strains in the animals’ digestive tracts and manure.

    This is the first study to take a broad sample of tetracycline resistance genes in a landscape dominated by hog farming, said principal investigator R.I. Mackie, a professor in the University of Illinois-Champaign department of animal sciences and an affiliate of the Institute for Genomic Biology.

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    Black Lung – Miners pay so you can get more coal

    The Pump Handle alerts us to a special report on coal miners and their lungs, not for the faint of heart, but something to keep in mind when you hear the phrases “Cheap Energy” and “coal” in one sentence, it’s not so cheap for these people.

    Black Lung: Dust Hasn’t Settled on Deadly Disease « The Pump Handle

    Louisville-Courier Journal reporters Laura Unger and Ralph Dunlop offer us the voices and faces of miners who are suffering from coal workers’ pneumoconiosis. Their special report, Black Lung: Dust Hasn’t Settled on Deadly Disease, includes an on-line version which features five compelling videos featuring 40- and 50-year old coal miners who are now suffering with the disabling lung disease. Mr. Danny Hall, 56, for example, who is still severely impaired despite receiving a lung transplant says “if I had to do over, I wouldn’t ever go into coal mining.”

  • Melamine – And Cyanuric Acid, A deadly pair?

    Like melamine, cyanuric acid is also used to artificially increase the nitrogen content of the food (detected as protein in protein tests).

    ScienceDaily: Pet Food Recall: How Melamine Impairs Kidney Function

    Perry Martos and colleagues in the Agriculture and Food Laboratory at Guelph’s Laboratory Services have found that melamine and cyanuric acid can react with one another to form crystals that may impair kidney function. Tests conducted at the University’s Animal Health Laboratory (AHL) and elsewhere have identified these crystal-like substances in the kidneys and urine of affected animals. The experiments conducted at the Agriculture and Food Laboratory showed that the chemical composition of the crystals that are formed when these two compounds interact matches the composition of urinary crystals removed from affected animals. Tests conducted at the University’s Laboratory and in the United States have identified the compounds as contaminants in gluten used to make a variety of pet food and treat products.

    Interestingly enough, the analytical test for cyanuric acid is to precipitate it with Melamine, so it is not as if these guys “discovered” this reaction, as the press release seems to intimate. There is also speculation that the  cyanuric acid was a metabolic byproduct of melamine from bacterial action, which is possible if the gluten was not stored correctly. It seems to me that Chinese manufacturers were using melamine or cyanuric acid to boost protein content for a while now. But it may have been only recently that they started adding both to the same food. The other possibility (and have you ever read the ingredients list in pet food, it takes a while!), is that one ingredient contained melamine, the other, cyanuric acid and when mixed…

    Either way, neither of these compounds belong in pet food.

  • Smoking bans

    If you followed the failed attempt in North Carolina this year to ban smoking in indoor public spaces, one of the so called arguments was the famous slippery slope one, that this was only a prelude to banning smoking “in the comfort of your own home”, and other attendant property rights arguments. Well, it turns out that there is an impromptu smoking ban in place in most homes already!

    Study: Smoking forbidden in most U.S. households – CNN.com

    Smoking is forbidden in nearly three out of four U.S. households, a dramatic increase from the 43 percent of homes that prohibited smoking a decade ago, the federal government reported Thursday.

    Before anyone makes the property rights argument that this “ban” is by choice, and not by government fiat, let me make it, and break it. Smoking falls into the category of occupational and reccreational exposure to pollution that harms and kills. It’s no different from lead in the water or smog as far as the non-smoker is concerned. So, property rights are not polluter rights, sorry.

    It’s only a matter of time before smoking indoors is considered completely and utterly unacceptable, kinda like smoking in airplanes!

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