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    Hog Factories are Evil Part 1232

    This rather interesting study tracks the movement and evolution of antibiotic resistance from hog cesspools (lagoons) caused by factory production (hog farming) of pig meat. You see, in order to pack that many hogs together and not cause them to keel over and die from disease, they have to be pumped full of antibiotics. Guess where the antibiotics end up? In their “refuse”.

    As always, I leave you with The Meatrix if you want to know more about factory farming.

    Antibiotic Resistance Tracked From Hog Farms to Groundwater

    The routine use of antibiotics in swine production can have unintended consequences, with antibiotic resistance genes sometimes leaking from waste lagoons into groundwater, according to new research from the University of Illinois.

    Researchers report that some genes found in hog waste lagoons are transferred, “like batons,” from one bacterial species to another. This migration across species and into new environments sometimes dilutes, and sometimes amplifies, genes conferring antibiotic resistance, they say.

    The new report, in the August issue of “Applied and Environmental Microbiology,” tracks the passage of tetracycline resistance genes from hog waste lagoons into groundwater wells at two Illinois swine facilities.

    Tetracycline is widely used in swine production. It is injected into the animals to treat or prevent disease, and is often used as an additive in hog feed to boost the animals’ growth.

    Its near-continuous use in some hog farms promotes the evolution of tetracycline-resistant strains in the animals’ digestive tracts and manure.

    This is the first study to take a broad sample of tetracycline resistance genes in a landscape dominated by hog farming, said principal investigator R.I. Mackie, a professor in the University of Illinois-Champaign department of animal sciences and an affiliate of the Institute for Genomic Biology.

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    Bisphenol A – Getting More Powerful Everyday

    So is it Mondays with Bisphenol?? You know what, the scary thing about this chemical is that its acute (short term, immediate) toxicity at high doses, which is the only safety testing that is ever done, does not correlate with all the subtle effects that are seen at low doses (chronic). Here’s another study where ambient level exposure to bisphenol A interferes with prostate cancer treatment by making the tumor cells androgen independent, so the standard testosterone deprivation therapy will not work any more.

    Environmental Health News: New Science

    A common plastic molecule to which virtually all Americans are exposed may interfere with the standard medical treatment for prostate cancer, according to new experiments with human prostate tumors implanted into mice. The doses of the plastic molecule, bisphenol A, were chosen specifically to be within the range of common human exposures. Tumor size and PSA levels were significantly greater in exposed animals just one month after treatment.

    One of the principal known sources of exposure to bisphenol A in the U.S. is through its use to make a resin that lines the majority of food cans sold in markets. These new results by Wetherill et al. suggest men concerned about prostate cancer may want to reduce their consumption of canned goods and their use of polycarbonate water bottles, another common source of exposure

    This is one powerful (if not actually more dangerous) chemical. it is so ubiquitous that finding a substitute is not going to be easy.

  • Melamine movin' on up the food chain

    The FDA mentioned recently that the melamine suspected of poisoning many cats had gotten into pig feed in California, well, it gets worse…

    Tuesday: Uh-Oh — North Carolina Public Radio WUNC

    The FDA announced this afternoon that thousands of hogs in NC and four or five other states are now under quarantine because they were fed tainted rice gluten. Hogs here and in CA have tested positive for melamine. No one knows yet whether it poses any dangers to humans who ate the hogs, but the feds say they’re trying to find out.

    At this point in time, I would consider any animal feed from China suspect. Way out of control, because we have no procedure for being proactive about these things…

    It won’t amount to much because melamine apparently does not affect humans as much as it seems to affect cats, but it is the utter lack of control of ingredients and raw materials that scares me. What else can sneak through? What if the next one is actually deadly to humans?

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    High fructose corn syrup makes you fat

    This well designed and well executed study provides rather conclusive proof that High Fructose Corn Syrup, the sweetener most commonly used in North America, makes you gain weight in a way not explained by calories alone. These rats gained more weight on HFCS compared to a sucrose (regular sugar) diet even though they were fed the same calories. The effect was seen in the short term and in the long term, and abdominal fat increased the most. Gut fat, if you did not know is related to the infamous metabolic syndrome, causing diabetes, hypertension, coronary disease, etc.

    High-fructose corn syrup (HFCS) accounts for as much as 40% of caloric sweeteners used in the United States. Some studies have shown that short-term access to HFCS can cause increased body weight, but the findings are mixed. The current study examined both short- and long-term effects of HFCS on body weight, body fat, and circulating triglycerides. In Experiment 1, male Sprague–Dawley rats were maintained for short term (8 weeks) on (1) 12 h/day of 8% HFCS, (2) 12 h/day 10% sucrose, (3) 24 h/day HFCS, all with ad libitum rodent chow, or (4) ad libitum chow alone. Rats with 12-h access to HFCS gained significantly more body weight than animals given equal access to 10% sucrose, even though they consumed the same number of total calories, but fewer calories from HFCS than sucrose. In Experiment 2, the long-term effects of HFCS on body weight and obesogenic parameters, as well as gender differences, were explored. Over the course of 6 or 7 months, both male and female rats with access to HFCS gained significantly more body weight than control groups. This increase in body weight with HFCS was accompanied by an increase in adipose fat, notably in the abdominal region, and elevated circulating triglyceride levels. Translated to humans, these results suggest that excessive consumption of HFCS may contribute to the incidence of obesity.

    Miriam E. Bocarsly, Elyse S. Powell, Nicole M. Avena, Bartley G. Hoebel. High-fructose corn syrup causes characteristic of obesity in rats: Increased body weight, body fat and triglyceride levels. Pharmacology Biochemistry and Behavior, 2010; DOI: 10.1016/j.pbb.2010.02.012

    For a more layman friendly summary of the article, read the sciencedaily release.

    Do reconsider your food habits to avoid HFCS. Note that this whole corn syrup boondongle is made possible by the US government’s insistence on providing billion dollar subsidies to its farmers to grow corn while imposing tariffs on cane sugar from the tropics to make it less attractive. Free trade, my A$$.

    Thanks to Tom Laskawy at grist for the blog post.

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    Arsenic in the News

    Professor wins $1M for arsenic filter – Yahoo! News

    The National Academy of Engineering announced Thursday that the 2007 Grainger Challenge Prize for Sustainability would go to Abul Hussam, a chemistry professor at George Mason University in Fairfax. Hussam’s invention is already in use today, preventing serious health problems in residents of the professor’s native Bangladesh.

    This British Geological Survey website provides a good primer to the problem. Some key points:

    1. Arsenic is very toxic
    2. Arsenic is naturally occurring in the shallow groundwater aquifers of Bengal and Bangladesh at a toxic level
    3. The surface water is contaminated with bacteria and was responsible for high infant mortality, so aid agencies in the ’70s encouraged the use of tube wells and other groundwater pumps. While this contributed to a decline in infant mortality from gastrointestinal infections, it also dosed unsuspecting people with disease causing levels of arsenic
    4. The technology for removal of arsenic is very well known. But most solutions require electricity/periodic maintenance/technical skills and are thus not universal or sustainable.
    5. Simplicity is the key. You can’t tell the people to not drink the water, it is the only clean water available. You can’t install water treatment plants, there is no running water, you can’t rely on solutions that are centralized.

    So with all that in mind, here’s what Prof. Hussam did:

    The Gold Award-winning SONO filter is a point-of-use method for removing arsenic from drinking water.  A top bucket is filled with locally available coarse river sand and a composite iron matrix (CIM).  The sand filters coarse particles and imparts mechanical stability, while the CIM removes inorganic arsenic.  The water then flows into a second bucket where it again filters through coarse river sand, then wood charcoal to remove organics, and finally through fine river sand and wet brick chips to remove fine particles and stabilize water flow.  The SONO filter is now manufactured and used in Bangladesh. That’s great, and easy!

    That’s pretty much freshman chemistry right there, further proof that most innovation does not need new science, only people willing to spend some time on problems that don’t necessarily get looked at.

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    Lasers shooting into irises

    I did not think my first minor surgery would involve someone shooting lasers to make holes in my iris. It sounds like more fun than it actually was, but was mostly painless and here I am, looking at a computer screen 3 hours later. My eyes feel like they’ve had about 5 hours of sleep, which is good considering they’re now sporting two brand new drain holes.

    Laser iridotomy is also performed prophylactically(preventively) on asymptomatic individuals with narrow angles and those with pigment dispersion. Individuals with a narrow angle are at higher risk of an acute angle closure, especially upon dilation of the eye

    http://www.surgeryencyclopedia.com/La-Pa/Laser-Iridotomy.html

    I also just started reading Bad Science by Ben Goldacre, which is about the use and misuse of the banner of science by a large group of people including nutritionists, pharmaceutical companies and “alternative” treatment specialists. It has a great chapter on the “placebo” effect, how much of it is culturally mediated, and how much doctor demeanour and confidence in their skills and outcome affects results. The doctor shooting holes in my eye was extremely confident in their skills and their results, and normally, my brain would be sending off all kinds of hubris warnings. In this case, their confidence reassured me a bit, and Bad Science definitely helped. It was also interesting to see a large section on homeopathy in the book, since I’ve written about my contact with homeopathy and felt that the cultural practices of a good homeopath can be of some use to people as long as they don’t go too far. The book confirmed some of that.